Welcome to Mayday!
Mayday is a workbench for visualization, analysis and storage of expression data.
It features a graphical user interface and supports the development and integration of existing and new analysis methods.
Mayday offers a variety of plug-ins, such as various interactive viewers, a connection to the R statistical environment, a connection to SQL-based databases, and different clustering methods, including phylogenetic methods.
In addition, so-called meta information objects are provided for annotation of the expression data allowing integration of data from different sources. This meta information can be used to enhance visualizations, such as in the enhanced heatmap visualization.
Written in the Java programming language, Mayday is extremely portable and runs on all platforms supporting the Java runtime environment 1.7.
Mayday is an ongoing project of the Integrative Transcriptomics research group led by Kay Nieselt.
If you use Mayday for your scientific work, please use the following citation.
Battke F, Symons S, Nieselt K.
Mayday – Integrative Analytics for Expression Data. BMC Bioinformatics 2010, 11:121 (doi:10.1186/1471-2105-11-121).
For Mayday SeaSight, please use the following citation.
Battke F, Nieselt K.
Mayday SeaSight: Combined Analysis of Deep Sequencing and Microarray Data. PLoS ONE 2011, 6(1): e16345 (doi:10.1371/journal.pone.0016345).
You can try Mayday right now without any installation!
The only requirement is a Oracle Java 7u72 (or higher) Webstart Environment. If you want to use the Mayday-R interface, a local installation of R is, of course, required.
We offer two versions:
Note: Currently there is a bug in the JNLP Class_loader under Java 8u91, which causes problems with the Webstart. If that is the case for you, please use the Standalone Version.
- Mayday stable webstart (Release 2.30)
– Recommended version
- Mayday experimental webstart (development version)
The experimental version contains new features and improvements, but not all functions have been tested as thoroughly as in the stable version.
- Mayday download version (Stable Release 2.30)
- Mayday download version (development version)
… after starting Mayday make sure that you set the plugin path under Mayday/Preferences to the ‘plugins’ subdirectory
*) On some machines, you will have to start Mayday twice to get the correct amount of memory. Mayday displays available memory in the bottom left status bar.
We have now integrated our new extension, SeaSight, allowing users to import raw microarray data together with mapped sequencing reads.
Data from different platforms can now be integrated and analyzed together using Mayday’s wealth of methods for visualization, data-mining, classification, and statistics.
Mayday SeaSight offers methods for computing expression values from mapped reads, raw microarray data import, background correction, normalization and summarization and linking microarray probes to genomic coordinates. These transformations can be combined in a user-friendly graphical interface to quickly construct powerful normalization pipelines.
Click here to start Mayday (including SeaSight).
We also prepared a small example dataset and a tutorial.
- Documentation for latest version of Mayday (2.14) with example data
- Introductory Guide to the core features (updated 2010-03-16)
- How-To: Mayday SeaSight (including sample data)
- How-To: Normalize Affymetrix GeneChips with Mayday SeaSight (see video)
- How-To: Pathway visualizations
- How-To: Mayday Processing Framework
- How-To: Machine Learning
- How-To: Mayday RLink – Installation and User’s Guide
- Mayday 2.0
- Mayday 1.1
- Plugin documentation
Mayday Source Code
The source code of Mayday is available here. A detailed instruction for importing the code into Eclipse will be announced as soon as possible.
For further information about Mayday please contact
André Hennig via hennig-$at$-informatik.uni-tuebingen.de.